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Selection of Tracers for (13)C-Metabolic Flux Analysis using Elementary Metabolite Units (EMU) Basis Vector Methodology

Metabolic flux analysis (MFA) is a powerful technique for elucidating in vivo fluxes in microbial and mammalian systems. A key step in (13)C-MFA is the selection of an appropriate isotopic tracer to observe fluxes in a proposed network model. Despite the importance of MFA in metabolic engineering an...

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Udgivet i:Metab Eng
Main Authors: Crown, Scott B., Antoniewicz, Maciek R.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474252/
https://ncbi.nlm.nih.gov/pubmed/22209989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2011.12.005
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