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Elementary Metabolite Units (EMU): a novel framework for modeling isotopic distributions

Metabolic Flux Analysis (MFA) has emerged as a tool of great significance for metabolic engineering and mammalian physiology. An important limitation of MFA, as carried out via stable isotope labeling and GC/MS and NMR measurements, is the large number of isotopomer or cumomer equations that need to...

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Detalhes bibliográficos
Main Authors: Antoniewicz, Maciek R., Kelleher, Joanne K., Stephanopoulos, Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1994654/
https://ncbi.nlm.nih.gov/pubmed/17088092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2006.09.001
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