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HDAC2 Inhibitor Valproic Acid Increases Radiation Sensitivity of Drug-Resistant Melanoma Cells

Resistance to anticancer drugs limits the effectiveness of chemotherapy in cancers. Melanoma cell lines B16F10C and A375C (parental) and B16F10R and A375R (drug-resistant sublines) were used to test radiation sensitization potential of valproic acid (VPA), an inhibitor of Histone deacetylase2 (HDAC2...

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Detalhes bibliográficos
Publicado no:Med Sci (Basel)
Main Authors: Kalal, Bhuvanesh Sukhlal, Pai, Vinitha Ramanath, Behera, Santosh Kumar, Somashekarappa, Hiriyur Mallaiah
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6473314/
https://ncbi.nlm.nih.gov/pubmed/30909413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medsci7030051
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