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Inhibition of ERK1/2 or AKT Activity Equally Enhances Radiation Sensitization in B16F10 Cells
BACKGROUND: The aim of the study was to evaluate the radiation sensitizing ability of ERK1/2, PI3K-AKT and JNK inhibitors in highly radiation resistant and metastatic B16F10 cells which carry wild-type Ras and Braf. METHODS: Mouse melanoma cell line B16F10 was exposed to 1.0, 2.0 and 3.0 Gy of elect...
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| Izdano u: | World J Oncol |
|---|---|
| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elmer Press
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5862079/ https://ncbi.nlm.nih.gov/pubmed/29581812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14740/wjon1088w |
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