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Accelerated Blood Clearance of Antibodies by Nanosized Click Antidotes

Long blood half-life is one of the advantages of antibodies over small molecule drugs. At the same time, prolonged half-life is a problem for imaging applications or in the case of antibody-induced toxicities. There is a substantial need for antidotes that can quickly clear antibodies from systemic...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Smith, Weston J., Wang, Guankui, Gaikwad, Hanmant, Vu, Vivian P., Groman, Ernest, Bourne, David W. A., Simberg, Dmitri
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472973/
https://ncbi.nlm.nih.gov/pubmed/30516974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.8b07003
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