Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children

Respiratory infections are common precursors to asthma exacerbations in children, but molecular immune responses that determine whether and how an infection causes an exacerbation are poorly understood. By using systems-scale network analysis, we identify repertoires of cellular transcriptional path...

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Vydáno v:Nat Immunol
Hlavní autoři: Altman, Matthew C., Gill, Michelle A., Whalen, Elizabeth, Babineau, Denise C., Shao, Baomei, Liu, Andrew H., Jepson, Brett, Gruchalla, Rebecca S., O’Connor, George T., Pongracic, Jacqueline A., Kercsmar, Carolyn M., Khurana Hershey, Gurjit K., Zoratti, Edward M., Johnson, Christine C., Teach, Stephen J., Kattan, Meyer, Bacharier, Leonard B., Beigelman, Avraham, Sigelman, Steve M., Presnell, Scott, Gern, James E., Gergen, Peter J., Wheatley, Lisa M., Togias, Alkis, Busse, William W., Jackson, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group US 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472965/
https://ncbi.nlm.nih.gov/pubmed/30962590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0347-8
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