Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children

Respiratory infections are common precursors to asthma exacerbations in children, but molecular immune responses that determine whether and how an infection causes an exacerbation are poorly understood. By using systems-scale network analysis, we identify repertoires of cellular transcriptional path...

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Gepubliceerd in:Nat Immunol
Hoofdauteurs: Altman, Matthew C., Gill, Michelle A., Whalen, Elizabeth, Babineau, Denise C., Shao, Baomei, Liu, Andrew H., Jepson, Brett, Gruchalla, Rebecca S., O’Connor, George T., Pongracic, Jacqueline A., Kercsmar, Carolyn M., Khurana Hershey, Gurjit K., Zoratti, Edward M., Johnson, Christine C., Teach, Stephen J., Kattan, Meyer, Bacharier, Leonard B., Beigelman, Avraham, Sigelman, Steve M., Presnell, Scott, Gern, James E., Gergen, Peter J., Wheatley, Lisa M., Togias, Alkis, Busse, William W., Jackson, Daniel J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group US 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472965/
https://ncbi.nlm.nih.gov/pubmed/30962590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0347-8
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