Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children

Respiratory infections are common precursors to asthma exacerbations in children, but molecular immune responses that determine whether and how an infection causes an exacerbation are poorly understood. By using systems-scale network analysis, we identify repertoires of cellular transcriptional path...

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Publicado no:Nat Immunol
Main Authors: Altman, Matthew C., Gill, Michelle A., Whalen, Elizabeth, Babineau, Denise C., Shao, Baomei, Liu, Andrew H., Jepson, Brett, Gruchalla, Rebecca S., O’Connor, George T., Pongracic, Jacqueline A., Kercsmar, Carolyn M., Khurana Hershey, Gurjit K., Zoratti, Edward M., Johnson, Christine C., Teach, Stephen J., Kattan, Meyer, Bacharier, Leonard B., Beigelman, Avraham, Sigelman, Steve M., Presnell, Scott, Gern, James E., Gergen, Peter J., Wheatley, Lisa M., Togias, Alkis, Busse, William W., Jackson, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472965/
https://ncbi.nlm.nih.gov/pubmed/30962590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0347-8
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