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Cellular Small Molecules Contribute to Twister Ribozyme Catalysis

The number of self-cleaving small ribozymes has increased sharply in recent years. Advances have been made in describing these ribozymes in terms of four catalytic strategies: α describes in-line attack, β describes neutralization of the non-bridging oxygens, γ describes activation of the nucleophil...

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Bibliographic Details
Published in:J Am Chem Soc
Main Authors: Messina, Kyle J., Bevilacqua, Philip C.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472948/
https://ncbi.nlm.nih.gov/pubmed/30102530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b06065
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