Hepatitis B e antigen induces the expansion of monocytic myeloid-derived suppressor cells to dampen T-cell function in chronic hepatitis B virus infection

Chronic hepatitis B virus (HBV) infection is associated with functionally impaired virus-specific T cell responses. Although the myeloid-derived suppressor cells (MDSCs) are known to play a critical role in impairing antiviral T cell responses, viral factors responsible for the expansion of MDSCs in...

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Foilsithe in:PLoS Pathog
Main Authors: Yang, Feifei, Yu, Xueping, Zhou, Chenliang, Mao, Richeng, Zhu, Mengqi, Zhu, Haoxiang, Ma, Zhenxuan, Mitra, Bidisha, Zhao, Gan, Huang, Yuxian, Guo, Haitao, Wang, Bin, Zhang, Jiming
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2019
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472891/
https://ncbi.nlm.nih.gov/pubmed/30998767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007690
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