The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection

Host innate immune defences play a critical role in restricting the intracellular propagation and pathogenesis of invading viral pathogens. Here we show that the histone H3.3 chaperone HIRA (histone cell cycle regulator) associates with promyelocytic leukaemia nuclear bodies (PML-NBs) to stimulate t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: McFarlane, Steven, Orr, Anne, Roberts, Ashley P. E., Conn, Kristen L., Iliev, Victor, Loney, Colin, da Silva Filipe, Ana, Smollett, Katherine, Gu, Quan, Robertson, Neil, Adams, Peter D., Rai, Taranjit Singh, Boutell, Chris
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472835/
https://ncbi.nlm.nih.gov/pubmed/30901352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007667
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