The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection

Host innate immune defences play a critical role in restricting the intracellular propagation and pathogenesis of invading viral pathogens. Here we show that the histone H3.3 chaperone HIRA (histone cell cycle regulator) associates with promyelocytic leukaemia nuclear bodies (PML-NBs) to stimulate t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Pathog
Egile Nagusiak: McFarlane, Steven, Orr, Anne, Roberts, Ashley P. E., Conn, Kristen L., Iliev, Victor, Loney, Colin, da Silva Filipe, Ana, Smollett, Katherine, Gu, Quan, Robertson, Neil, Adams, Peter D., Rai, Taranjit Singh, Boutell, Chris
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2019
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472835/
https://ncbi.nlm.nih.gov/pubmed/30901352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007667
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