Genetically engineered macrophages expressing IFN-γ restore alveolar immune function in scid mice

Reversal of immunodeficiency in the lung by gene therapy is limited in part by the difficulty of transfecting lung cells in vivo. Many options exist for successfully transfecting cells in vitro, but they are not easily adapted to the in vivo condition. To overcome this limitation, we transduced macr...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wu, Min, Hussain, Shabbir, He, Ying-Hui, Pasula, Rajamouli, Smith, Patricia A., Martin, William J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC64726/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11724936/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251451498
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