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Genetically engineered macrophages expressing IFN-γ restore alveolar immune function in scid mice
Reversal of immunodeficiency in the lung by gene therapy is limited in part by the difficulty of transfecting lung cells in vivo. Many options exist for successfully transfecting cells in vitro, but they are not easily adapted to the in vivo condition. To overcome this limitation, we transduced macr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC64726/ https://ncbi.nlm.nih.gov/pubmed/11724936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251451498 |
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