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Complement activation in factor D-deficient mice

To assess the contribution of the alternative pathway in complement activation and host defense and its possible role in the regulation of systemic energy balance in vivo, factor D-deficient mice were generated by gene targeting. The mutant mice have no apparent abnormality in development and their...

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Bibliografiske detaljer
Main Authors: Xu, Yuanyuan, Ma, Minghe, Ippolito, Gregory C., Schroeder, Harry W., Carroll, Michael C., Volanakis, John E.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC64724/
https://ncbi.nlm.nih.gov/pubmed/11724962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261428398
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