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Self-organization of Plk4 regulates symmetry breaking in centriole duplication

During centriole duplication, a single daughter centriole is formed next to the mother centriole. The molecular mechanism that determines a single duplication site remains a long-standing question. Here, we show that intrinsic self-organization of Plk4 is implicated in symmetry breaking in the proce...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Yamamoto, Shohei, Kitagawa, Daiju
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472344/
https://ncbi.nlm.nih.gov/pubmed/31000710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09847-x
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