miR-146a-5p expression is upregulated by the CXCR4 antagonist TN14003 and attenuates SDF-1-induced cartilage degradation

Osteoarthritis (OA) is an aseptic inflammatory disease which is associated with the stromal cell-derived factor 1/C-X-C chemokine receptor type 4 (SDF-1/CXCR4) axis. Accumulating studies have identified numbers of microRNAs (miRNAs) that serve important roles in the pathogenesis of OA. However, whet...

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Vydáno v:Mol Med Rep
Hlavní autoři: Jia, Di, Li, Yanlin, Han, Rui, Wang, Kun, Cai, Guofeng, He, Chuan, Yang, Lingjian
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2019
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6472139/
https://ncbi.nlm.nih.gov/pubmed/30942441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2019.10076
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