Attenuation of osteoarthritis via blockade of the SDF-1/CXCR4 signaling pathway

INTRODUCTION: This study was performed to evaluate the attenuation of osteoarthritic (OA) pathogenesis via disruption of the stromal cell-derived factor-1 (SDF-1)/C-X-C chemokine receptor type 4 (CXCR4) signaling with AMD3100 in a guinea pig OA model. METHODS: OA chondrocytes and cartilage explants...

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Bibliografiske detaljer
Main Authors: Wei, Fangyuan, Moore, Douglas C, Li, Yanlin, Zhang, Ge, Wei, Xiaochun, Lee, Joseph K, Wei, Lei
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580571/
https://ncbi.nlm.nih.gov/pubmed/22849584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3930
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