Population pharmacokinetics and pharmacodynamics of the artesunate–mefloquine fixed dose combination for the treatment of uncomplicated falciparum malaria in African children

BACKGROUND: The World Health Organization (WHO) recommends combinations of an artemisinin derivative plus an anti-malarial drug of longer half-life as treatment options for uncomplicated Plasmodium falciparum infections. In Africa, artesunate–mefloquine (ASMQ) is an infrequently used artemisinin-bas...

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Udgivet i:Malar J
Main Authors: Guidi, Monia, Mercier, Thomas, Aouri, Manel, Decosterd, Laurent A., Csajka, Chantal, Ogutu, Bernhards, Carn, Gwénaëlle, Kiechel, Jean-René
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471806/
https://ncbi.nlm.nih.gov/pubmed/30999915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2754-6
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