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A Dynamic Bayesian Network model for the simulation of Amyotrophic Lateral Sclerosis progression

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease progressively affecting upper and lower motor neurons in the brain and spinal cord. Mean life expectancy is three to five years, with paralysis of muscles, respiratory failure and loss of vital functions bein...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Zandonà, Alessandro, Vasta, Rosario, Chiò, Adriano, Di Camillo, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471677/
https://ncbi.nlm.nih.gov/pubmed/30999865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2692-x
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