SENP1, but not fetal hemoglobin, differentiates Andean highlanders with chronic mountain sickness from healthy individuals among Andean highlanders

Chronic mountain sickness (CMS) results from chronic hypoxia. It is unclear why certain highlanders develop CMS. We hypothesized that modest increases in fetal hemoglobin (HbF) are associated with lower CMS severity. In this cross-sectional study, we found that HbF levels were normal (median = 0.4%)...

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Vydáno v:Exp Hematol
Hlavní autoři: Hsieh, Matthew M., Callacondo, David, Rojas-Camayo, Jose, Quesada-Olarte, Jose, Wang, Xunde, Uchida, Naoya, Maric, Irina, Remaley, Alan T., Leon-Velarde, Fabiola, Villafuerte, Francisco C., Tisdale, John F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471513/
https://ncbi.nlm.nih.gov/pubmed/26952840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2016.02.010
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