Increased hypoxic proliferative response and gene expression in erythroid progenitor cells of Andean highlanders with chronic mountain sickness

Excessive erythrocytosis (EE) is the main sign of chronic mountain sickness (CMS), a maladaptive clinical syndrome prevalent in Andean and other high-altitude populations worldwide. The pathophysiological mechanism of EE is still controversial, as physiological variability of systemic respiratory, c...

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Pubblicato in:Am J Physiol Regul Integr Comp Physiol
Autori principali: Bermudez, Daniela, Azad, Priti, Figueroa-Mujíca, Rómulo, Vizcardo-Galindo, Gustavo, Corante, Noemí, Guerra-Giraldez, Cristina, Haddad, Gabriel G., Villafuerte, Francisco C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985794/
https://ncbi.nlm.nih.gov/pubmed/31617751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00250.2019
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