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Plasma Rich in Growth Factors (PRGF) Disrupt the Blood-Brain Barrier Integrity and Elevate Amyloid Pathology in the Brains of 5XFAD Mice

Alzheimer’s disease (AD) is the most common neurodegenerative disorder affecting 5.4 million people in the United States. Currently approved pharmacologic interventions for AD are limited to symptomatic improvement, not affecting the underlying pathology. Therefore, the search for novel therapeutic...

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Библиографические подробности
Опубликовано в: :Int J Mol Sci
Главные авторы: Duong, Quoc-Viet, Kintzing, Margia L., Kintzing, William E., Abdallah, Ihab M., Brannen, Andrew D., Kaddoumi, Amal
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471393/
https://ncbi.nlm.nih.gov/pubmed/30934587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20061489
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