Physalis peruviana-Derived 4β-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo

Deregulation of the Wnt signaling pathway leads to colorectal cancer progression. Natural dietary compounds serve as promising candidates for development as chemopreventive agents by suppressing the Wnt/β-catenin signaling pathway. Physalis peruviana-derived 4βHWE showed a significant inhibitory act...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Ye, Zhen-Nan, Yuan, Feng, Liu, Jie-Qing, Peng, Xing-Rong, An, Tao, Li, Xue, Kong, Ling-Mei, Qiu, Ming-Hua, Li, Yan
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6471161/
https://ncbi.nlm.nih.gov/pubmed/30909473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24061146
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