Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling

Wnt signaling pathway is aberrantly activated in a variety of cancers, especially in colorectal cancer and small molecule antagonists of Wnt/β-catenin signaling are attractive candidates for developing effective therapeutics. In the present study, we identified Bisleuconothine A, a bisindole alkaloi...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Kong, Ling-Mei, Feng, Tao, Wang, Yuan-Yuan, Li, Xing-Yao, Ye, Zhen-Nan, An, Tao, Qing, Chen, Luo, Xiao-Dong, Li, Yan
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891114/
https://ncbi.nlm.nih.gov/pubmed/26862734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7190
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