Investigation of Crystallization and Salt Formation of Poorly Water-Soluble Telmisartan for Enhanced Solubility

The crystal changes and salt formation of poorly water-soluble telmisartan (TEL) in various solvents were investigated for enhanced solubility, stability and crystallinity. Polymorphic behaviors of TEL were characterized by dispersing in distilled water, acetone, acetonitrile, DMSO, or ethanol using...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Park, Chulhun, Meghani, Nileshkumar M., Shin, Yongkwan, Oh, Euichaul, Park, Jun-Bom, Cui, Jing-Hao, Cao, Qing-Ri, Tran, Thao Truong-Dinh, Tran, Phuong Ha-Lien, Lee, Beom-Jin
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470926/
https://ncbi.nlm.nih.gov/pubmed/30823389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11030102
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