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Design and Synthesis of New Quinoxaline Derivatives as Anticancer Agents and Apoptotic Inducers

The quinoxaline scaffold is a promising platform for the discovery of active chemotherapeutic agents. Three series of quinoxaline derivatives were synthesized and biologically evaluated against three tumor cell lines (HCT116 human colon carcinoma, HepG2, liver hepatocellular carcinoma and MCF-7, hum...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: El Newahie, Aliya M. S., Nissan, Yassin M., Ismail, Nasser S. M., Abou El Ella, Dalal A., Khojah, Sohair M., Abouzid, Khaled A.M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470675/
https://ncbi.nlm.nih.gov/pubmed/30934622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24061175
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