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MYC Oncogene Contributions to Release of Cell Cycle Brakes

Promotion of the cell cycle is a major oncogenic mechanism of the oncogene c-MYC (MYC). MYC promotes the cell cycle by not only activating or inducing cyclins and CDKs but also through the downregulation or the impairment of the activity of a set of proteins that act as cell-cycle brakes. This revie...

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Detalles Bibliográficos
Publicado en:Genes (Basel)
Main Authors: García-Gutiérrez, Lucía, Delgado, María Dolores, León, Javier
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470592/
https://ncbi.nlm.nih.gov/pubmed/30909496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10030244
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