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Understanding Immune Evasion and Therapeutic Targeting Associated with PD-1/PD-L1 Pathway in Diffuse Large B-cell Lymphoma

In tumor microenvironment, the programmed death 1 (PD-1) immune checkpoint has a crucial role of mechanism of T cell exhaustion leading to tumor evasion. Ligands of PD-1, programmed death ligand 1/2 (PD-L1/L2) are over-expressed in tumor cells and participate in prolonged tumor progression and survi...

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Publicat a:Int J Mol Sci
Autors principals: Song, Moo-Kon, Park, Byeong-Bae, Uhm, Jieun
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470519/
https://ncbi.nlm.nih.gov/pubmed/30884772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20061326
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