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Understanding Splenomegaly in Myelofibrosis: Association with Molecular Pathogenesis

Myelofibrosis (MF) is a clinical manifestation of chronic BCR-ABL1-negative chronic myeloproliferative neoplasms. Splenomegaly is one of the major clinical manifestations of MF and is directly linked to splenic extramedullary hematopoiesis (EMH). EMH is associated with abnormal trafficking patterns...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Song, Moo-Kon, Park, Byeong-Bae, Uhm, Ji-Eun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877759/
https://ncbi.nlm.nih.gov/pubmed/29562644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19030898
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