Human Mitotic Centromere-Associated Kinesin Is Targeted by MicroRNA 485-5p/181c and Prognosticates Poor Survivability of Breast Cancer

PURPOSE: This study aims to evaluate the prognostic value of human Mitotic Centromere-Associated Kinesin (MCAK), a microtubule-dependent molecular motor, in breast cancers. The posttranscriptional regulation of MCAK by microRNAs will also be explored. METHODS: The large-scale gene expression dataset...

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Pubblicato in:J Oncol
Autori principali: Lu, Huajun, Wang, Chaoqun, Xue, Lijun, Zhang, Qi, Luh, Frank, Wang, Jianghai, Lin, Tiffany G., Yen, Yun, Liu, Xiyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470426/
https://ncbi.nlm.nih.gov/pubmed/31073307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2316237
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