Overexpression of BRCA1 in Neural Stem Cells Enhances Cell Survival and Functional Recovery after Transplantation into Experimental Ischemic Stroke

Transplantation of neural stem cells (NSCs) is a promising therapy for ischemic stroke. However, the effectiveness of this approach is limited by grafted cell death. Breast cancer susceptibility protein 1 (BRCA1) could suppress apoptosis in neural progenitors and modulate oxidative stress in neurons...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Xu, Pengfei, Shi, Xiaolei, Zhang, Xiaohao, Liu, Qian, Xie, Yi, Hong, Ye, Li, Juanji, Peng, Mengna, Liu, Xinfeng, Xu, Gelin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470423/
https://ncbi.nlm.nih.gov/pubmed/31073355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/8739730
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