Microglial TREM-1 receptor mediates neuroinflammatory injury via interaction with SYK in experimental ischemic stroke

Neuroinflammation is initiated in response to ischemic stroke, generally with the hallmarks of microglial activation and collateral brain injury contributed by robust inflammatory effects. Triggering receptor expressed on myeloid cells (TREM)-1, an amplifier of the innate immune response, is a criti...

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Vydáno v:Cell Death Dis
Hlavní autoři: Xu, Pengfei, Zhang, Xiaohao, Liu, Qian, Xie, Yi, Shi, Xiaolei, Chen, Jingjing, Li, Yunzi, Guo, Hongquan, Sun, Rui, Hong, Ye, Liu, Xinfeng, Xu, Gelin
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642102/
https://ncbi.nlm.nih.gov/pubmed/31324751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1777-9
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