Extensive mechanical tension promotes annulus fibrosus cell senescence through suppressing cellular autophagy

Background: Mechanical load contributes a lot to the initiation and progression of disc degeneration. Annulus fibrosus (AF) cell biology under mechanical tension remains largely unclear. Objective: The present study was aimed to investigate AF cell senescence under mechanical tension and the potenti...

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Bibliographic Details
Published in:Biosci Rep
Main Authors: Zhao, Liang, Tian, Baofang, Xu, Qing, Zhang, Cunxin, Zhang, Luo, Fang, Haolin
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470409/
https://ncbi.nlm.nih.gov/pubmed/30910846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20190163
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