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Rapamycin prevents the intervertebral disc degeneration via inhibiting differentiation and senescence of annulus fibrosus cells

The effects of bleomycin and rapamycin on cellular senescence and differentiation of rabbit annulus fibrosus stem cells (AFSCs) were investigated using a cell culture model. The results showed that bleomycin induced cellular senescence in AFSCs as evidenced by senescence-associated secretory phenoty...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Gao, Changhong, Ning, Bin, Sang, Chenglin, Zhang, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811247/
https://ncbi.nlm.nih.gov/pubmed/29348392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101364
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