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Role of TREK-1 in Health and Disease, Focus on the Central Nervous System

TREK-1 is the most studied background K(2P) channel. Its main role is to control cell excitability and maintain the membrane potential below the threshold of depolarization. TREK-1 is multi-regulated by a variety of physical and chemical stimuli which makes it a very promising and challenging target...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Djillani, Alaeddine, Mazella, Jean, Heurteaux, Catherine, Borsotto, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470294/
https://ncbi.nlm.nih.gov/pubmed/31031627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00379
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