The LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer

LMO4 belongs to a family of LIM-only transcriptional regulators, the first two members of which are oncoproteins in acute T cell leukemia. We have explored a role for LMO4, initially described as a human breast tumor autoantigen, in developing mammary epithelium and breast oncogenesis. Lmo4 was expr...

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Autori principali: Visvader, Jane E., Venter, Deon, Hahm, Kyungmin, Santamaria, Margaret, Sum, Eleanor Y. M., O'Reilly, Lorraine, White, David, Williams, Rachael, Armes, Jane, Lindeman, Geoffrey J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC64702/
https://ncbi.nlm.nih.gov/pubmed/11734645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251547698
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