Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer

The zinc finger protein LMO4 is overexpressed in a high proportion of breast carcinomas. Here, we report that overexpression of a mouse mammary tumor virus (MMTV)-Lmo4 transgene in the mouse mammary gland elicits hyperplasia and mammary intraepithelial neoplasia or adenosquamous carcinoma in two tra...

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Detalhes bibliográficos
Main Authors: Sum, Eleanor Y. M., Segara, Davendra, Duscio, Belinda, Bath, Mary L., Field, Andrew S., Sutherland, Robert L., Lindeman, Geoffrey J., Visvader, Jane E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140463/
https://ncbi.nlm.nih.gov/pubmed/15897450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502990102
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