Integrative Approach to Reveal Cell Type Specificity and Gene Candidates for Psoriatic Arthritis Outside the MHC

We recently conducted a large association analysis to compare the genetic profiles between patients with psoriatic arthritis (PsA) and cutaneous-only psoriasis (PsC). Despite including over 7,000 genotyped patients, only the MHC achieved genome-wide significance. In this study, we hypothesized that...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Patrick, Matthew T., Stuart, Philip E., Raja, Kalpana, Chi, Sunyi, He, Zhi, Voorhees, John J., Tejasvi, Trilokraj, Gudjonsson, Johann E., Kahlenberg, J. Michelle, Chandran, Vinod, Rahman, Proton, Gladman, Dafna D., Nair, Rajan P., Elder, James T., Tsoi, Lam C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470186/
https://ncbi.nlm.nih.gov/pubmed/31031798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00304
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