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Substrate Binding Regulates Redox Signaling in Human DNA Primase
Generation of daughter strands during DNA replication requires the action of DNA primase to synthesize an initial short RNA primer on the single-stranded DNA template. Primase is a heterodimeric enzyme containing two domains whose activity must be coordinated during primer synthesis: an RNA polymera...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6470046/ https://ncbi.nlm.nih.gov/pubmed/30433774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b09914 |
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