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Ferritin Exhibits Michaelis-Menten Behavior with Oxygen but not with Iron During Iron Oxidation and Core Mineralization

The excessively high and inconsistent literature values for K(m, Fe) and K(m, O2) prompted us to examine the iron oxidation kinetics in ferritin, the major iron storage protein in mammals, and to determine whether a traditional Michaelis-Menten enzymatic behavior is obeyed. The kinetics of Fe(II) ox...

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Bibliografische gegevens
Gepubliceerd in:Metallomics
Hoofdauteurs: Bou-Abdallah, Fadi, Flint, Nicholas, Wilkinson, Tyler, Smith, Samantha, Srivastava, Ayush Kumar, Poli, Maura, Arosio, Paolo, Melman, Artem
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470027/
https://ncbi.nlm.nih.gov/pubmed/30720039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9mt00001a
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