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Identification and Molecular Characterization of PPARδ as a Novel Target for Covalent Modification by 15-deoxy-Δ(12, 14)-prostaglandin J(2)

PPARδ belongs to the peroxisome proliferator-activated receptor (PPAR) family of nuclear receptors. Upon activation by an agonist, PPARδ controls a variety of physiological processes via regulation of its target genes. 15-deoxy-Δ(12,14)-PGJ(2) (15d-PGJ(2)) is a cyclopentenone prostaglandin that feat...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Reddy, Aravind T., Lakshmi, Sowmya P., Banno, Asoka, Reddy, Raju C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6470001/
https://ncbi.nlm.nih.gov/pubmed/30398845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00584
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