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Two Pathways of p27(Kip1) Degradation Are Required for Murine Lymphoma Driven by Myc and EBV Latent Membrane Protein 2A

Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A), expressed in EBV latency, contributes to Burkitt lymphoma (BL) development in a murine model by acting as a constitutively active B cell receptor (BCR) mimic. Mice expressing both LMP2A and MYC transgenes (LMP2A/λ-MYC) develop tumors signi...

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Bibliografiska uppgifter
I publikationen:mBio
Huvudupphovsmän: Sora, Richard P., Ikeda, Masato, Longnecker, Richard
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469971/
https://ncbi.nlm.nih.gov/pubmed/30992353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00548-19
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