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Two Pathways of p27(Kip1) Degradation Are Required for Murine Lymphoma Driven by Myc and EBV Latent Membrane Protein 2A
Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A), expressed in EBV latency, contributes to Burkitt lymphoma (BL) development in a murine model by acting as a constitutively active B cell receptor (BCR) mimic. Mice expressing both LMP2A and MYC transgenes (LMP2A/λ-MYC) develop tumors signi...
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| Veröffentlicht in: | mBio |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6469971/ https://ncbi.nlm.nih.gov/pubmed/30992353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00548-19 |
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