Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies

The D-2-hydroxyacid dehydrogenase (2HADH) family illustrates a complex evolutionary history with multiple lateral gene transfers and gene duplications and losses. As a result, the exact functional annotation of individual members can be extrapolated to a very limited extent. Here, we revise the prev...

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Udgivet i:Biochemistry
Main Authors: Kutner, Jan, Shabalin, Ivan G., Matelska, Dorota, Handing, Katarzyna B., Gasiorowska, Olga, Sroka, Piotr, Gorna, Maria W., Ginalski, Krzysztof, Wozniak, Krzysztof, Minor, Wladek
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469932/
https://ncbi.nlm.nih.gov/pubmed/29309127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01137
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