Laxative effect of repeated Daiokanzoto is attributable to decrease in aquaporin-3 expression in the colon

Daiokanzoto (DKT) exerts its laxative effect via colonic inflammation caused by sennoside A in Daio (rhubarb). Previously, we showed that the laxative effect of sennoside A is related to decreased aquaporin-3 (AQP3) expression in mucosal epithelial cells due to colonic inflammation. We also found th...

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Veröffentlicht in:J Nat Med
Hauptverfasser: Kon, Risako, Yamamura, Miho, Matsunaga, Yukari, Kimura, Hiroshi, Minami, Moe, Kato, Saki, Ikarashi, Nobutomo, Sugiyama, Kiyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Singapore 2018
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469848/
https://ncbi.nlm.nih.gov/pubmed/29380109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11418-018-1174-1
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