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Epithelial DNA methyltransferase-1 regulates cell survival, growth and maturation in developing prostatic buds

DNA methyltransferase 1 (DNMT1) is required for embryogenesis but roles in late forming organ systems including the prostate, which emerges from the urethral epithelium, have not been fully examined. We used a targeted genetic approach involving a Shhcre recombinase to demonstrate requirement of epi...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Joseph, Diya B, Chandrashekar, Anoop S, Abler, Lisa L, Chu, Li-Fang, Thomson, James A, Vezina, Chad M
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469356/
https://ncbi.nlm.nih.gov/pubmed/30659795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.01.011
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