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In vivo replacement of damaged bladder urothelium by Wolffian duct epithelial cells

The bladder’s remarkable regenerative capacity had been thought to derive exclusively from its own progenitors. While examining consequences of DNA methyltransferase 1 (Dnmt1) inactivation in mouse embryonic bladder epithelium, we made the surprising discovery that Wolffian duct epithelial cells can...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Joseph, Diya B., Chandrashekar, Anoop S., Abler, Lisa L., Chu, Li-Fang, Thomson, James A., Mendelsohn, Cathy, Vezina, Chad M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099915/
https://ncbi.nlm.nih.gov/pubmed/30061411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802966115
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