2-Nitroimidazole-Furanoside Derivatives for Hypoxia Imaging—Investigation of Nucleoside Transporter Interaction, (18)F-Labeling and Preclinical PET Imaging

The benefits of PET imaging of tumor hypoxia in patient management has been demonstrated in many examples and with various tracers over the last years. Although, the optimal hypoxia imaging agent has yet to be found, 2-nitroimidazole (azomycin) sugar derivatives—mimicking nucleosides—have proven the...

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Vydáno v:Pharmaceuticals (Basel)
Hlavní autoři: Maier, Florian C., Schweifer, Anna, Damaraju, Vijaya L., Cass, Carol E., Bowden, Gregory D., Ehrlichmann, Walter, Kneilling, Manfred, Pichler, Bernd J., Hammerschmidt, Friedrich, Reischl, Gerald
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469291/
https://ncbi.nlm.nih.gov/pubmed/30781409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12010031
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