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2-Nitroimidazole-Furanoside Derivatives for Hypoxia Imaging—Investigation of Nucleoside Transporter Interaction, (18)F-Labeling and Preclinical PET Imaging

The benefits of PET imaging of tumor hypoxia in patient management has been demonstrated in many examples and with various tracers over the last years. Although, the optimal hypoxia imaging agent has yet to be found, 2-nitroimidazole (azomycin) sugar derivatives—mimicking nucleosides—have proven the...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Maier, Florian C., Schweifer, Anna, Damaraju, Vijaya L., Cass, Carol E., Bowden, Gregory D., Ehrlichmann, Walter, Kneilling, Manfred, Pichler, Bernd J., Hammerschmidt, Friedrich, Reischl, Gerald
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469291/
https://ncbi.nlm.nih.gov/pubmed/30781409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph12010031
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