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Overexpression of HHLA2 in human clear cell renal cell carcinoma is significantly associated with poor survival of the patients

BACKGROUND: It is well known that human clear cell renal cell carcinoma (ccRCC) is a highly immunogenic and chemo-resistant tumor. Recently, emerging data suggest that the immune checkpoint blockade therapy is an important breakthrough in the treatment against ccRCC. HHLA2, a recently reported membe...

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Publicado en:Cancer Cell Int
Autores principales: Chen, Lujun, Zhu, Dawei, Feng, Jun, Zhou, You, Wang, Qi, Feng, Huijing, Zhang, Junping, Jiang, Jingting
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469208/
https://ncbi.nlm.nih.gov/pubmed/31015801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0813-2
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